Exploring the minimum bactericidal concentration and time kill kinetics of benzothiophene derivatives in gram-positive bacteria

To determine the minimum bactericidal concentration (MBC) and confirm minimum inhibitory concentration (MIC) of a benzothiophene derivative (#34) using the microdilution and
macrodilution assay against two gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis.
● To explore the time and dose dependence bactericidal/bacteriostatic activity of the compound #34 using time kill assay.
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Abstract/Description: To determine the minimum bactericidal concentration (MBC) and confirm minimum inhibitory concentration (MIC) of a benzothiophene derivative (#34) using the microdilution and macrodilution assay against two gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis. ● To explore the time and dose dependence bactericidal/bacteriostatic activity of the compound #34 using time kill assay.
Subject(s): Undergraduate Research
Novel antibiotics
Date Issued: 2021