Analyzing CSF tau concentrations in Alzheimer's disease and control patients

The purpose of this project is to establish a phage-based biomarker screening assay to recognize AD in human blood and cerebrospinal samples. Specifically, I will be completing ELISA screening of available phage that were identified in prior semesters to identify candidate phage for for further testing.
Phase 1 is to identify phages that recognize PTM changes in tau, and phase 2 is to test the phage in a large array of clinical samples of human blood and cerebrospinal fluid.
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Abstract/Description: The purpose of this project is to establish a phage-based biomarker screening assay to recognize AD in human blood and cerebrospinal samples. Specifically, I will be completing ELISA screening of available phage that were identified in prior semesters to identify candidate phage for for further testing. Phase 1 is to identify phages that recognize PTM changes in tau, and phase 2 is to test the phage in a large array of clinical samples of human blood and cerebrospinal fluid.
Subject(s): Molecular Neuropharmacology and Biomarker Discovery Research Lab
Undergraduate Research
CSF tau concentrations
Alzheimer's Disease (AD)
Date Issued: 2021